Made In USA Safe for use on any age of pet. Zymox Otic Enzymatic Solution With .5% hydrocortisone Highly effective in the management of acute and chronic otitis due to bacterial, fungal and yeast infections. Works without antibiotics. The powerful enzymatic action of patented LP3 Enzyme system naturally cleans and disinfects while destroying even the most resistant microbes. Broad spectrum, tested proven against: Pseudomonas Malassezia pachydermatitis Methicillin Resistant Staphylococcus aureus Staphylococcus aureus Candida albicans Proteus mirabilis Eschericha coli Streptococcus intermedius Streptococcus pyogenes ZYMOX Ear Cleanser provides an effective, non-toxic way to manage dirty ears. The addition of Lacoperoxidase, Lactoferrin and Lysozyme, which have natural bio-active properties for mild microbe control, plus gentle cleaning surfactants, makes Zymox Ear Cleanser perfect for cleaning dirty ears. Does not contain harsh chemicals or cleaners to irritate sensitive ears. Leaves ears smelling fresh.